B12 and MIC Injectable

Medication Description

B12, Methionine, Inositol and Choline injectable compound in an amber vial (dosage will vary per your prescription)

Compounded Drug Forms: Subcutaneous injection

What is B12?

Vitamin B12 is essential for energy production and helps keep your metabolism running efficiently.

What is MIC?

The “MIC” stands for Methionine, Inositol, and Choline, which are essential nutrients.

What should I tell my health care provider before I take this medicine?

• Liver or kidney disease
• Diabetes or metabolic disorders
• Cardiovascular conditions
• Cobalamin (B12) or sulfonamide allergy
• Leber’s disease or other optic nerve conditions
• Pregnancy or breastfeeding
• Polycythemia vera
• Hypokalemia (low potassium)
• History of cancer

Tell your doctor about all your current medications:

• Metformin (may reduce B12 absorption)
• Proton pump inhibitors or H2 blockers
• Chloramphenicol
• Anticoagulants (blood thinners)
• Any injectable medications

How should I use this medicine?

Follow the package directions provided by the pharmacy and by your prescriber. Your dosage is based on your medical condition and response to therapy. Follow the dosing schedule provided carefully. Injectable medications should be given subcutaneously or intramuscularly as directed by your healthcare provider. See recommended administration guide for further instruction.

What if I miss a dose?

• If you miss a dose within 3 days of the scheduled weekly dose, administer it as soon as possible.
• If more than 3 days have passed since the missed dose, skip the missed dose, and continue with your regular dosing schedule.
• Do not take double the dose at once.

What should I watch for while using this medicine?

• Signs of allergic reaction: Difficulty breathing, swelling of the face or throat, widespread hives, or a rapid heart rate.
• Signs of infection at the injection site: Increasing redness, warmth, swelling, or discharge.
• Low potassium signs: Muscle weakness, cramps, or irregular heartbeat — particularly important in patients on diuretics.
• Neurological changes: New or worsening numbness, tingling, or weakness.
• Persistent or severe symptoms: Nausea, vomiting, or headaches that last more than a few days or are unusually intense.

What side effects may I notice from receiving this medicine?

Side effects that may occur and may go away as your body gets used to the medication include:

• Mild pain, redness, swelling, or itching at the injection site.
• Nausea or mild digestive upset.
• Headache.
• Mild flushing (warm or tingling sensation under the skin).
• Dizziness or lightheadedness.
• Fatigue or, rarely, sleep disturbance.

What serious side effects prompt immediate attention?

Contact your doctor immediately or seek medical attention if you experience:

• Allergic Reactions: Symptoms such as hives, rash, facial or throat swelling, difficulty breathing, or rapid heartbeat warrant immediate medical care.
• Severe Injection Site Reaction: Increasing pain, warmth, pus, or spreading redness may indicate infection.
• Neurological Symptoms: Numbness, tingling, or weakness not related to the injection site.
• Low potassium (hypokalemia): Muscle weakness, cramping, or irregular heartbeat, particularly early in treatment.
• Persistent or Severe Symptoms: Ongoing nausea, vomiting, or severe headaches beyond the initial adjustment phase.

You may experience side effects not listed. Contact your doctor with questions. An allergic reaction to this medication is unlikely but seek medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, and/or trouble breathing.

Contraindications and Cautions

Individuals who are pregnant or breastfeeding, have a known allergy to cobalamin (Vitamin B12), or have pre-existing liver, kidney, or optic nerve conditions. These patients also have significant interactions with certain medications.

What may interact with this medicine?

This is not a complete list of all possible interactions. Always inform your doctor and pharmacist of all medications, supplements, and herbal products you take, especially before starting or stopping any new medication.

Additional Information

• Store compounded B12/MIC injections under refrigeration (36–46°F / 2–8°C) and keep protected from light.
• Check the solution before each use — do not use if cloudy, discolored, or if particles are visible.
• Do not share this medication with others to whom it was not prescribed.
• Keep out of reach of children and pets.
• Do not use after Beyond Use Date. Discard remainder of vial 28 days after first puncture.
• If an overdose is suspected, contact your local poison control center at 1-800-222-1222 or go to the nearest emergency room.
• Do not flush down the toilet or pour down a drain. Check with your pharmacist if you have questions about the best way to dispose of medications. There may be a drug take-back program in your area.
• Dispose of all used needles and syringes immediately in an FDA-cleared sharps container. Visit safeneedledisposal.org to find a drop-off location.

Reporting Side Effects

If you have any questions concerning this or any of your medications, a pharmacist is available during normal business hours to answer your questions. You can report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medication or any other medication. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does not include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. For questions about the source of any of the information provided herein, pharmacists at Pharmacy are available. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.